Evaluation of membrane-based therapeutic plasma exchange as adjunctive treatment for immune-mediated hematologic disorders in dogs.

ABSTRACT:

Background

Therapeutic plasma exchange (TPE) has been used increasingly to treat immunological diseases in dogs, although data concerning its efficacy are lacking.

Hypothesis/objectives

To describe the clinic and the outcome of dogs with immune-mediated hematological disorders (IMHD) treated with membrane filtration TPE.

Animals

One hundred forty-six dogs diagnosed with IMHD, including 17 dogs treated with and 129 control dogs treated without TPE.

Methods

Retrospective study of cases selected with a search of all medical records for dogs diagnosed with IMHD (2010-2019). Primary outcomes included the assessment of safety and efficacy of adjunctive TPE compared to medical treatment alone.

Results

The TPE group included 7 dogs with immune-mediated hemolytic

SUBMITTER: Francey T 

PROVIDER: S-EPMC7995402 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature