A carbon nanotubes based in situ multifunctional power assist system for restoring failed heart function.

ABSTRACT:

Background

End-stage heart failure is a major risk of mortality. The conductive super-aligned carbon nanotubes sheets (SA-CNTs) has been applied to restore the structure and function of injured myocardium through tissue engineering, and developed as efficient cardiac pacing electrodes. However, the interfacial interaction between SA-CNTs and the surface cells is unclear, and it remains challenge to restore the diminished contraction for a seriously damaged heart.

Results

A concept of a multifunctional power assist system (MPS) capable of multipoint pacing and contraction assisting is proposed. This device is designed to work with the host heart and does not contact blood, thus avoiding long-term anticoagulation required in current therapies. Pacing electrode constructed by S

SUBMITTER: Xu Q 

PROVIDER: S-EPMC7995575 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature