Understanding implementability in clinical trials: a pragmatic review and concept map.

ABSTRACT:

Background

The translation of evidence from clinical trials into practice is complex. One approach to facilitating this translation is to consider the 'implementability' of trials as they are designed and conducted. Implementability of trials refers to characteristics of the design, execution and reporting of a late-phase clinical trial that can influence the capacity for the evidence generated by that trial to be implemented. On behalf of the Australian Clinical Trials Alliance (ACTA), the national peak body representing networks of clinician researchers conducting investigator-initiated clinical trials, we conducted a pragmatic literature review to develop a concept map of implementability.

Methods

Documents were included in the review if they related to the design, conduc

SUBMITTER: Cumpston MS 

PROVIDER: S-EPMC7995762 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature