Impact of reported NSAID "allergies" on opioid use disorder in back pain.

ABSTRACT:

Background

It is crucial to identify patients at highest risk for opioid use disorder (OUD) and to address challenges in reducing opioid use. Reported nonsteroidal anti-inflammatory drug (NSAID) allergies may predispose to use of stronger pain medications and potentially to OUD.

Objective

We sought to investigate the clinical impact of reported NSAID allergy on OUD in patients with chronic back pain.

Methods

We conducted a retrospective study of adults receiving care at a tertiary health care system from January 1, 2013, to December 31, 2018. Back pain and OUD were identified using administrative data algorithms. We used propensity score matching and logistic regression to estimate the impact of self-reported NSAID adverse drug reactions (ADRs) on risk of OUD, adjusti

SUBMITTER: Li L 

PROVIDER: S-EPMC7995999 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature