Leptospirosis diagnosis among patients suspected of dengue fever in Brazil.

ABSTRACT:

Background

The early symptoms of leptospirosis and dengue fever are difficult to distinguish and can cause diagnostic confusion. Due to the large dengue epidemics that has occurred in Brazil in recent years, it is possible that cases of leptospirosis were unreported. Therefore, we performed a retrospective study to detect leptospirosis in patients who were tested for dengue, but whose laboratory diagnoses were negative.

Methods

Sera samples from 2,017 patients from 48 cities located in the central region of São Paulo state, Brazil, were studied. All samples were subjected to the microscopic agglutination test (MAT), 305 of which were taken from patients five days or less since the onset of symptoms, and were additionally subjected to real-time polymerase chain reaction (PCR)

SUBMITTER: Fornazari F 

PROVIDER: S-EPMC7996315 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature