Ontology highlight
ABSTRACT:
SUBMITTER: Engeman E
PROVIDER: S-EPMC7996583 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Engeman Emily E Freyberger Helen R HR Corey Brendan W BW Ward Amanda M AM He Yunxiu Y Nikolich Mikeljon P MP Filippov Andrey A AA Tyner Stuart D SD Jacobs Anna C AC
Pharmaceuticals (Basel, Switzerland) 20210225 3
Multidrug-resistant (MDR) <i>Pseudomonas aeruginosa</i> infections pose a serious health threat. Bacteriophage-antibiotic combination therapy is a promising candidate for combating these infections. A 5-phage <i>P. aeruginosa</i> cocktail, PAM2H, was tested in combination with antibiotics (ceftazidime, ciprofloxacin, gentamicin, meropenem) to determine if PAM2H enhances antibiotic activity. Combination treatment in vitro resulted in a significant increase in susceptibility of MDR strains to anti ...[more]