Visible Lights Combined with Photosensitizing Compounds Are Effective against Candida albicans Biofilms.

ABSTRACT: Fungal infections are increasing in prevalence worldwide, especially in immunocompromised individuals. Given the emergence of drug-resistant fungi and the fact that there are only three major classes of antifungal drugs available to treat invasive fungal infections, there is a need to develop alternative therapeutic strategies effective against fungal infections. Candida albicans is a commensal of the human microbiota that is also one of the most common fungal pathogens isolated from clinical settings. C. albicans possesses several virulence traits that contribute to its pathogenicity, including the ability to form drug-resistant biofilms, which can make C. albicans infections particularly challenging to treat. Here, we explored red, green, and blue visible lights alone and in combination

SUBMITTER: Bapat P 

PROVIDER: S-EPMC7996876 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature