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Evaluation of six anti-SARS-CoV-2 antibody test kits and practical approaches to optimize the diagnostic performance.


ABSTRACT: In an investigation of six anti-SARS-CoV-2 antibody kits with different target antigen and methodology, each kit showed comparable performance. As false-positive reactions occurred independently with different kits, specificity increased to 100% when pairs of kits were used. With three-kit combination, both sensitivity (99.1%) and specificity (100%) increased.

SUBMITTER: Ko JH 

PROVIDER: S-EPMC7997140 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature