Nanocellulose/PEGDA Aerogels with Tunable Poisson's Ratio Fabricated by Stereolithography for Mouse Bone Marrow Mesenchymal Stem Cell Culture.

ABSTRACT: In this study, nanocellulose aerogels with a tunable Poisson's ratio were fabricated. Tissue engineering scaffolds with a tunable Poisson's ratio may be better able to simulate the mechanical behavior of natural tissues. A mixture of cellulose nanofibers (CNFs) and polyethylene glycol diacrylate (PEGDA) was used as the raw material to prepare CNF/PEGDA aerogels with a multiscale pore structure through a combination of stereolithography (SLA) and freeze-drying. The aerogels were fabricated with a regular macropore network structure and a random and homogeneous distribution of micropores. The macropore structure of the scaffolds could be customized through SLA, which resulted in scaffolds that exhibited one of three different mechanical behaviors: positive Poisson's ratio (PPR), negative Poi

SUBMITTER: Tang A 

PROVIDER: S-EPMC7997334 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature