Association of Thrombus Aspiration With Time and Mortality Among Patients With ST-Segment Elevation Myocardial Infarction: A Post Hoc Analysis of the Randomized TOTAL Trial.

ABSTRACT:

Importance

Patients with shorter ischemic times have a greater viable myocardium and may derive greater benefit from thrombus aspiration.

Objective

To study the association of thrombus aspiration with outcomes among patients presenting with ST-segment elevation myocardial infarction (STEMI) based on time.

Design, setting, and participants

The TOTAL (Thrombectomy With PCI vs PCI Alone in Patients with STEMI) trial was an international randomized clinical trial of 10 732 patients with STEMI undergoing primary percutaneous coronary intervention (PCI) within 12 hours of symptom onset. Patients were recruited between August 5, 2010, and July 25, 2014, and were followed up for 1 year. Data analysis was performed from February 22, 2019, to January 5, 2021.

Interventions</

SUBMITTER: Moxham R 

PROVIDER: S-EPMC7998077 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature