Whole Genome Sequence Analysis of Brucella abortus Isolates from Various Regions of South Africa.

ABSTRACT: The availability of whole genome sequences in public databases permits genome-wide comparative studies of various bacterial species. Whole genome sequence-single nucleotide polymorphisms (WGS-SNP) analysis has been used in recent studies and allows the discrimination of various Brucella species and strains. In the present study, 13 Brucella spp. strains from cattle of various locations in provinces of South Africa were typed and discriminated. WGS-SNP analysis indicated a maximum pairwise distance ranging from 4 to 77 single nucleotide polymorphisms (SNPs) between the South African Brucella abortus virulent field strains. Moreover, it was shown that the South African B. abortus strains grouped closely to B. abortus strains from Mozambique and Zimbabwe, as

SUBMITTER: Ledwaba MB 

PROVIDER: S-EPMC7998772 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature