Direct Flavonoid-Focused Chemical Comparison among Three Epimedium Plants by Online Liquid Extraction-High Performance Liquid Chromatography-Tandem Mass Spectrometry.

ABSTRACT: It is usually a tedious task to profile the chemical composition of a given herbal medicine (HM) using high performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) due to the time-consuming sample preparation and laborious post-acquisition data processing procedures. Even worse, some labile compounds may face degradation risks when exposed to organic solvents for a relatively long period. As one of the most popular HMs, the promising therapeutic benefits of Epimedii Herba (Chinese name: Yinyanghuo) are well defined; however, the chemical profile, and in particular those flavonoids that have been claimed to be responsible for the efficacy, remains largely unknown. Attempts are devoted here to achieve direct LC-MS measurement and efficient post-acquisition data processing, and

SUBMITTER: Xu X 

PROVIDER: S-EPMC7998785 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature