Resting and exercise haemodynamics in relation to six-minute walk test in patients with heart failure and preserved ejection fraction.

ABSTRACT:

Aims

Patients with heart failure and preserved ejection fraction (HFpEF) are characterized by functional impairment and an abnormal haemodynamic response to exercise. The six-minute walk test (6MWT) serves as a standardized test for functional capacity quantification in heart failure patients, and is associated with cardiovascular outcomes. However, as the association between 6MWT and haemodynamic parameters during rest and exercise in HFpEF patients is unknown, we sought to elucidate this relationship.

Methods and results

Overall, 64 patients enrolled in the REDUCE LAP-HF trial completed a 6MWT at baseline. Univariate and multivariable linear regression models were used to assess the associations between 6MWT and measured or derived haemodynamic variables at baseline, durin

SUBMITTER: Wolsk E 

PROVIDER: S-EPMC8000591 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature