Plasma B Vitamers: Population Epidemiology and Parent-Child Concordance in Children and Adults.

ABSTRACT:

Scope

B vitamers are co-enzymes involved in key physiological processes including energy production, one-carbon, and macronutrient metabolism. Studies profiling B vitamers simultaneously in parent-child dyads are scarce. Profiling B vitamers in parent-child dyads enables an insightful determination of gene-environment contributions to their circulating concentrations. We aimed to characterise: (a) parent-child dyad concordance, (b) generation (children versus adults), (c) age (within the adult subgroup (age range 28-71 years)) and (d) sex differences in plasma B vitamer concentrations in the CheckPoint study of Australian children.

Methods and results

1166 children (11 ± 0.5 years, 51% female) and 1324 parents (44 ± 5.1 years, 87% female) took part in a biomedical assessment

SUBMITTER: Andraos S 

PROVIDER: S-EPMC8001009 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature