New Triterpene Glycosides from the Far Eastern Starfish Solaster pacificus and Their Biological Activity.

ABSTRACT: Three new triterpene glycosides, pacificusosides A-C (1-3), and three previously known triterpene glycosides, cucumariosides C₁ (4), C₂ (5), and A₁₀ (6), were isolated from the alcoholic extract of the Far Eastern starfish Solaster pacificus. The structures of 1-3 were elucidated by extensive NMR and ESIMS techniques and chemical transformations. Compound 1 has a novel, unique structure, containing an aldehyde group of side chains in its triterpene aglycon. This structural fragment has not previously been found in the sea cucumber triterpene glycosides or starfish steroidal glycosides. Probably, pacificusoside A (1) is a product of the metabolism of the glycoside obtained through dietary

SUBMITTER: Malyarenko TV 

PROVIDER: S-EPMC8001898 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature