Plasmonic Layer as a Localized Temperature Control Element for Surface Plasmonic Resonance-Based Sensors.

ABSTRACT: Surface plasmon resonance (SPR) sensing is a well-established high-sensitivity, label-free and real-time detection technique for biomolecular interaction study. Its primary working principle consists of the measurement of the optical refractive index of the medium that is in close vicinity of the sensor surface. Bio-functionalization techniques allow biomolecular events to be located in such a way. Since optical refractive indices of any medium varies with the temperature, the place where the measurement takes place shall be within a temperature-controlled environment in order to ensure any temperature fluctuation is interpreted as a biomolecular event. Since the SPR measurement probes the sensed medium within the penetration depth of the plasmonic wave, which is less or in the order of 1

SUBMITTER: Ganesan S 

PROVIDER: S-EPMC8001950 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature