Epidemiological Differences in the Impact of COVID-19 Vaccination in the United States and China.

ABSTRACT: This study forecasts Coronavirus Disease 2019 (COVID-19) vaccination impact in two countries at different epidemic phases, the United States (US) and China. We assessed the impact of both a vaccine that prevents infection (VE_S of 95%) and a vaccine that prevents only disease (VE_P of 95%) through mathematical modeling. For VE_S of 95% and gradual easing of restrictions, vaccination in the US reduced the peak incidence of infection, disease, and death by >55% and cumulative incidence by >32% and in China by >77% and >65%, respectively. Nearly three vaccinations were needed to avert one infection in the US, but only one was needed in China. For VE_P of 95%, vaccination benefits were half those for VE_S of 9

SUBMITTER: Makhoul M 

PROVIDER: S-EPMC8002114 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature