PepFun: Open Source Protocols for Peptide-Related Computational Analysis.

ABSTRACT: Peptide research has increased during the last years due to their applications as biomarkers, therapeutic alternatives or as antigenic sub-units in vaccines. The implementation of computational resources have facilitated the identification of novel sequences, the prediction of properties, and the modelling of structures. However, there is still a lack of open source protocols that enable their straightforward analysis. Here, we present PepFun, a compilation of bioinformatics and cheminformatics functionalities that are easy to implement and customize for studying peptides at different levels: sequence, structure and their interactions with proteins. PepFun enables calculating multiple characteristics for massive sets of peptide sequences, and obtaining different structural observables deri

SUBMITTER: Ochoa R 

PROVIDER: S-EPMC8002403 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature