Ontology highlight
ABSTRACT:
SUBMITTER: Reynaud D
PROVIDER: S-EPMC8002561 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Reynaud Deborah D Sergent Frederic F Abi Nahed Roland R Traboulsi Wael W Collet Constance C Marquette Christel C Hoffmann Pascale P Balboni Gianfranco G Zhou Qun-Yong QY Murthi Padma P Benharouga Mohamed M Alfaidy Nadia N
Biomedicines 20210317 3
Endocrine gland derived vascular endothelial growth factor (EG-VEGF) is a canonical member of the prokineticin (PROKs) family. It acts via the two G-protein coupled receptors, namely PROKR1 and PROKR2. We have recently demonstrated that EG-VEGF is highly expressed in the human placenta; contributes to placental vascularization and growth and that its aberrant expression is associated with pregnancy pathologies including preeclampsia and fetal growth restriction. These findings strongly suggested ...[more]