External Validation and Extension of a Clinical Score for the Discrimination of Type 2 Myocardial Infarction.

ABSTRACT:

Background

The early non-invasive discrimination of Type 2 versus Type 1 Myocardial Infarction (T2MI, T1MI) is a major unmet clinical need. We aimed to externally validate a recently derived clinical score (Neumann) combing female sex, no radiating chest pain, and high-sensitivity cardiac troponin I (hs-cTnI) concentration ≤40.8 ng/L.

Methods

Patients presenting with acute chest discomfort to the emergency department were prospectively enrolled into an international multicenter diagnostic study. The final diagnoses of T2MI and T1MI were centrally adjudicated by two independent cardiologists using all information including cardiac imaging and serial measurements of hs-cTnT/I according to the fourth universal definition of MI. Model performance for T2MI diagnosis was assessed

SUBMITTER: Nestelberger T 

PROVIDER: S-EPMC8003225 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature