Matrix-Assisted DOSY for Analysis of Indole Alkaloid Mixtures.

ABSTRACT: Diffusion-ordered spectroscopy (DOSY) is a powerful tool for investigating mixtures and identifying peaks of chemical components. However, similar diffusion coefficients of the components, particularly for complex mixtures that contain crowded resonances, limit resolution and restrict application of the DOSY technique. In this paper, matrix-assisted DOSY were used to explore whether the diffusion resolution of a complex model involving indole alkaloid mixtures can be realized. Furthermore, we investigated the influence of different factors on the separation effect. The results showed that the changes in diffusion coefficient differences were achieved more obviously when using sodium dodecyl sulfate (SDS) micelles as the matrix. In addition, we also found that increasing the concentration o

SUBMITTER: You YL 

PROVIDER: S-EPMC8003906 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature