Sex differences in the link between blood cobalt concentrations and insulin resistance in adults without diabetes.

ABSTRACT:

Background

Little is known about the effects of environmental cobalt exposure on insulin resistance (IR) in the general adult population. We investigated the association between cobalt concentration and IR.

Methods

A total of 1281 subjects aged more than 20 years with complete blood cobalt data were identified from the National Health and Nutrition Examination Survey (NHANES) 2015-2016 cycle. Blood cobalt levels were analyzed for their association with IR among all populations and subgroups by sex. Regression coefficients and 95% confidence intervals (CIs) of blood cobalt concentrations in association with fasting glucose, insulin and homeostatic model assessment of insulin resistance (HOMA-IR) were estimated using multivariate linear regression after adjusting for age, sex,

SUBMITTER: Chen Y 

PROVIDER: S-EPMC8005238 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature