More Favorable Short and Long-Term Outcomes for Screen-Detected Colorectal Cancer Patients.

ABSTRACT:

Background

Screening significantly reduces mortality from colorectal cancer (CRC). Screen detected (SD) tumors associate with better prognosis, even at later stage, compared to non-screen detected (NSD) tumors. We aimed to evaluate the association between diagnostic modality (SD vs. NSD) and short- and long-term outcomes of patients undergoing surgery for CRC.

Materials and methods

This retrospective cohort study involved patients aged 50-69 years, residing in Veneto, Italy, who underwent curative-intent surgery for CRC between 2006 and 2018. The clinical multi-institutional dataset was linked with the screening dataset in order to define diagnostic modality (SD vs. NSD). Short- and long-term outcomes were compared between the two groups.

Results

Of 1,360 patients inc

SUBMITTER: Spolverato G 

PROVIDER: S-EPMC8005726 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature