The association of standard Kt/V and surface area-normalized standard Kt/V with clinical outcomes in hemodialysis patients.

ABSTRACT:

Introduction

A previous study demonstrated that the surface area-normalized standard Kt/V (SAstdKt/V) was better associated with mortality than standard Kt/V (stdKt/V). This study investigates the association of SAstdKt/V and stdKt/V with mortality, anemia, and hypoalbuminemia in a larger patient cohort with a longer follow-up period.

Methods

We included adult patients on thrice-weekly hemodialysis in the USRDS database and excluded amputated patients. StdKt/V and SAstdKt/V were calculated from the available single-pool Kt/V. Patients were categorized into five groups according to their stdKt/V and SAstdKt/V: <2.00, 2.00-2.19, 2.20-2.39, 2.40-2.59, and ≥2.60. Hazard ratios (HR) and odds ratios (OR) were calculated using Cox and logistic regression analysis respectively.

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SUBMITTER: Pattharanitima P 

PROVIDER: S-EPMC8006157 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature