Antecedent febrile illness and occurrence of stroke in West Africa: The SIREN study.

ABSTRACT:

Background

Acute infections have been posited as potential precipitants or triggers of the occurrence of stroke among adults with traditional vascular risk factors. We evaluated associations between stroke occurrence and reported febrile illness within 4 weeks (potential antecedent infections) among West Africans.

Methods

The Stroke Investigative Research and Educational Network (SIREN) is a multicenter, case-control study involving 15 sites in Ghana and Nigeria. Cases include adults aged ≥18 years with radiologically confirmed strokes. Controls were stroke-free adults matched with cased by age, gender and ethnicity. Detailed evaluations for vascular, lifestyle and psychosocial factors were performed. Participants were asked for evidence of any febrile illness within the pas

SUBMITTER: Sarfo FS 

PROVIDER: S-EPMC8006213 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature