A quality control pipeline for probabilistic reconstruction of white-matter pathways.

ABSTRACT:

Background

One of the most well-validated tools for DTI data analysis is TRACULA, part of the FreeSurfer software. TRACULA automatically segments 18 major white matter (WM) tracts. Occasionally, tracts may be only partially reconstructed, thus requiring intervention to avoid biasing analyses. A majority of studies have not reported any quality control procedures and those that have tend to discard partially reconstructed tracts from group analyses if they cannot be salvaged during TRACULA reinitialization.

New method

We propose a semi-automated method to improve the detection and recovery of incomplete WM tracts. We detail several steps to maximize the quality of preprocessed DTI data. The steps include: (1) a visual inspection of eddy current corrected diffusion weighted im

SUBMITTER: He X 

PROVIDER: S-EPMC8006796 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature