Oropharyngeal meningococcal carriage in children and adolescents, a single center study in Buenos Aires, Argentina.

ABSTRACT:

Background

Neisseria meningitidis (Nm) pharyngeal carriage is a necessary condition for invasive disease. We present the first carriage study in children in Buenos Aires, Argentina, considering 2017 as a transition year. Aims: to assess the rate of Nm carriage, to determine genogroup, clonal complex and outer membrane protein distribution, to determine carriage risk factors by age.

Methods

Cross-sectional study including children 1-17 yrs, at Ricardo Gutiérrez Children's Hospital in Buenos Aires 2017. Oro-pharyngeal swabs were taken and cultured within a short time after collection. Genogroup was determined by PCR and clonal complex by MLST. Categorical variables were analyzed.

Results

A total of 1,751 children were included. Group 1: 943 children 1-9 yrs, 38 Nm were

SUBMITTER: Gentile A 

PROVIDER: S-EPMC8006983 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature