Potentiated inhibition of Trichoderma virens and other environmental fungi by new biocide combinations.

ABSTRACT: Fungi cause diverse, serious socio-economic problems, including biodeterioration of valuable products and materials that spawns a biocides industry worth ~$11 billion globally. To help combat environmental fungi that commonly colonise material products, this study tested the hypothesis that combination of an approved fungicide with diverse agents approved by the FDA (Food and Drug Administration) could reveal potent combinatorial activities with promise for fungicidal applications. The strategy to use approved compounds lowers potential development risks for any effective combinations. A high-throughput assay of 1280 FDA-approved compounds was conducted to find those that potentiate the effect of iodopropynyl-butyl-carbamate (IPBC) on the growth of Trichoderma virens; IPBC is one of the tw

SUBMITTER: Vallieres C 

PROVIDER: S-EPMC8007513 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature