Total metabolic lesion volume of lymph nodes measured by ¹⁸F-FDG PET/CT: a new predictor of macrophage activation syndrome in adult-onset Still's disease.

ABSTRACT:

Background

To investigate the potential utility of quantitative parameters obtained by ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT) in the assessment of disease severity and the occurrence of macrophage activation syndrome (MAS) in adult-onset Still's disease (AOSD).

Methods

Fifty-seven patients with AOSD who underwent pre-treatment ¹⁸F-FDG PET/CT were recruited in this study and compared with 60 age- and sex-matched healthy controls. Clinical features and laboratory data were recorded. The systemic score was assessed to determine the disease severity. The maximal standardized uptake value (SUV_max), metabolic lesion volume (MLV), and total lesion glycolysis (TLG) were used to evaluate the

SUBMITTER: Wan L 

PROVIDER: S-EPMC8008587 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature