Unknown

Dataset Information

0

Evidence for current circulation of an ancient West Nile virus strain (NY99) in Brazil.

ABSTRACT: In Brazil, West Nile virus (WNV) was first detected, in 2018, in horses with neurological disease. We report the first case of WNV infection in a horse from Ceará state and the complete genome sequence of an isolate from Espírito Santo state. Both infections occurred in 2019. WNV was isolated from the tissues of a horse with neurological signs in Espírito Santo and sequenced by MiSeq. Phylogenetic analysis revealed that the isolate belongs to lineage 1a, clustering with the NY99 strain, a strain that has not circulated in the USA since 2005. Our findings reinforce the hypothesis that WNV has been silently circulating in Brazil for many years.

SUBMITTER: Siconelli MJL 

PROVIDER: S-EPMC8008906 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

<h4>Introduction</h4>In Brazil, West Nile virus (WNV) was first detected, in 2018, in horses with neurological disease.<h4>Aim</h4>We report the first case of WNV infection in a horse from Ceará state and the complete genome sequence of an isolate from Espírito Santo state. Both infections occurred in 2019.<h4>Methods</h4>WNV was isolated from the tissues of a horse with neurological signs in Espírito Santo and sequenced by MiSeq.<h4>Results</h4>Phylogenetic analysis revealed that the isolate be  ...[more]