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Hydrosulfide-selective ChemFETs for aqueous H2S/HS- measurement.

ABSTRACT: We have prepared and characterized hydrosulfide-selective ChemFET devices based on a nitrile butadiene rubber membrane containing tetraoctylammonium nitrate as a chemical recognition element that is applied to commercially available field-effect transistors. The sensors have fast (120 s) reversible responses, selectivity over other biologically relevant thiol-containing species, detection limits of 8 mM, and a detection range from approximately 5 to 500 mM. Sensitivities are shown to be 53 mV per decade at pH 8. Use of this compact, benchtop sensor platform requires little training - only the ability to measure DC voltage, which can be accomplished with a conventional multimeter or a simple analog data acquisition device paired with a personal computer. To the best of our knowledge, this report describes the first example of direct potentiometric measurement of the hydrosulfide ion in water.

SUBMITTER: Sherbow TJ

PROVIDER: S-EPMC8009328 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature

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Hydrosulfide-selective ChemFETs for aqueous H2S/HS- measurement.

Sherbow Tobias J TJ Kuhl Grace M GM Lindquist Grace A GA Levine Jordan D JD Pluth Michael D MD Johnson Darren W DW Fontenot Sean A SA

Sensing and Bio-Sensing Research 20201229

We have prepared and characterized hydrosulfide-selective ChemFET devices based on a nitrile butadiene rubber membrane containing tetraoctylammonium nitrate as a chemical recognition element that is applied to commercially available field-effect transistors. The sensors have fast (120 s) reversible responses, selectivity over other biologically relevant thiol-containing species, detection limits of 8 mM, and a detection range from approximately 5 to 500 mM. Sensitivities are shown to be 53 mV pe ...[more]

PMID: 33791191

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