Predicting microbial growth dynamics in response to nutrient availability.

ABSTRACT: Developing mathematical models to accurately predict microbial growth dynamics remains a key challenge in ecology, evolution, biotechnology, and public health. To reproduce and grow, microbes need to take up essential nutrients from the environment, and mathematical models classically assume that the nutrient uptake rate is a saturating function of the nutrient concentration. In nature, microbes experience different levels of nutrient availability at all environmental scales, yet parameters shaping the nutrient uptake function are commonly estimated for a single initial nutrient concentration. This hampers the models from accurately capturing microbial dynamics when the environmental conditions change. To address this problem, we conduct growth experiments for a range of micro-organisms, i

SUBMITTER: Nev OA 

PROVIDER: S-EPMC8009381 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature