Acute tryptophan depletion in healthy subjects increases preferences for negative reciprocity.

ABSTRACT: Reciprocity motivates to reward those who are kind (= positive reciprocity) and to punish those who are unkind (= negative reciprocity). The neurotransmitter serotonin (5-HT) modulates human behavior in numerous social situations, such as retaliation in response to perceived unfairness. In a placebo-controlled study, we used acute tryptophan depletion (ATD) to investigate the influence of available serotonin on choice behavior and reciprocity in the Hawk-Dove game. This game illustrates a conflict situation and incorporates two potential strategies: the cooperative Dove strategy and the uncooperative, more aggressive Hawk strategy. After strategic choices, we elicited the subjects' expectations (= beliefs) regarding the opponent's choices and controlled for risk preferences and current moo

SUBMITTER: Bengart P 

PROVIDER: S-EPMC8009398 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature