Combining viral genetic and animal mobility network data to unravel peste des petits ruminants transmission dynamics in West Africa.

ABSTRACT: Peste des petits ruminants (PPR) is a deadly viral disease that mainly affects small domestic ruminants. This disease threaten global food security and rural economy but its control is complicated notably because of extensive, poorly monitored animal movements in infected regions. Here we combined the largest PPR virus genetic and animal mobility network data ever collected in a single region to improve our understanding of PPR endemic transmission dynamics in West African countries. Phylogenetic analyses identified the presence of multiple PPRV genetic clades that may be considered as part of different transmission networks evolving in parallel in West Africa. A strong correlation was found between virus genetic distance and network-related distances. Viruses sampled within the same mobil

SUBMITTER: Bataille A 

PROVIDER: S-EPMC8009415 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature