Acute Effects of Ketamine Infusion on Postoperative Mood Scores in Patients Undergoing Dilation and Curettage: A Randomized Double-Blind Controlled Study.

ABSTRACT:

Background

Emotional and psychological effects following abortion are more common than physical side effects and can range from mild regret to more serious complications such as depression. In the last decade, it has been suggested that low dose of ketamine is a fast-acting antidepressant.

Purpose

The aim of this study was to investigate the impact of intraoperative ketamine infusion on postoperative mood score in patients undergoing Dilation and Curettage (D&C) under spinal anesthesia. We hypothesized that a single low-dose administration of ketamine infusion during D&C surgery can improve mood scores in the immediate postoperative period.

Methods

A prospective, randomized, double-blind, parallel-group, placebo-controlled trial. The study included a total of 60 patie

SUBMITTER: Mostafa RH 

PROVIDER: S-EPMC8009713 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature