Integration of multi-omics approaches for functional characterization of muscle related selective sweep genes in Nanchukmacdon.

ABSTRACT: Pig as a food source serves daily dietary demand to a wide population around the world. Preference of meat depends on various factors with muscle play the central role. In this regards, selective breeding abled us to develop "Nanchukmacdon" a pig breeds with an enhanced variety of meat and high fertility rate. To identify genomic regions under selection we performed whole-genome resequencing, transcriptome, and whole-genome bisulfite sequencing from Nanchukmacdon muscles samples and used published data for three other breeds such as Landrace, Duroc, Jeju native pig and analyzed the functional characterization of candidate genes. In this study, we present a comprehensive approach to identify candidate genes by using multi-omics approaches. We performed two different methods XP-EHH, XP-CLR t

SUBMITTER: Arora D 

PROVIDER: S-EPMC8009959 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature