Optimizing HIV retesting during pregnancy and postpartum in four countries: a cost-effectiveness analysis.

ABSTRACT:

Introduction

HIV retesting during late pregnancy and breastfeeding can help detect new maternal infections and prevent mother-to-child HIV transmission (MTCT), but the optimal timing and cost-effectiveness of maternal retesting remain uncertain.

Methods

We constructed deterministic models to assess the health and economic impact of maternal HIV retesting on a hypothetical population of pregnant women, following initial testing in pregnancy, on MTCT in four countries: South Africa and Kenya (high/intermediate HIV prevalence), and Colombia and Ukraine (low HIV prevalence). We evaluated six scenarios with varying retesting frequencies from late in antenatal care (ANC) through nine months postpartum. We compared strategies using incremental cost-effectiveness ratios (ICERs) over

SUBMITTER: Meisner J 

PROVIDER: S-EPMC8010369 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature