Impact of CT convolution kernel on robustness of radiomic features for different lung diseases and tissue types.

ABSTRACT:

Objectives

In this study, we aimed to assess the impact of different CT reconstruction kernels on the stability of radiomic features and the transferability between different diseases and tissue types. Three lung diseases were evaluated, i.e. non-small cell lung cancer (NSCLC), malignant pleural mesothelioma (MPM) and interstitial lung disease related to systemic sclerosis (SSc-ILD) as well as four different tissue types, i.e. primary tumor, largest involved lymph node ipsilateral and contralateral lung.

Methods

Pre-treatment non-contrast enhanced CT scans from 23 NSCLC, 10 MPM and 12 SSc-ILD patients were collected retrospectively. For each patient, CT scans were reconstructed using smooth and sharp kernel in filtered back projection. The regions of interest (

SUBMITTER: Denzler S 

PROVIDER: S-EPMC8010534 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature