Spot-Scanning Hadron Arc (SHArc) Therapy: A Study With Light and Heavy Ions.

ABSTRACT:

Purpose

To evaluate the clinical potential of spot-scanning hadron arc (SHArc) therapy with a heavy-ion gantry.

Methods and materials

A series of in silico studies was conducted via treatment plan optimization in FRoG and the RayStation TPS to compare SHArc therapy against reference plans using conventional techniques with single, parallel-opposed, and 3-field configurations for 3 clinical particle beams (protons [p], helium [⁴He], and carbon [¹²C] ions). Tests were performed on water-equivalent cylindrical phantoms for simple targets and clinical-like scenarios with an organ-at-risk in proximity of the target. Effective dose and dose-averaged linear energy transfer (LET_D) distributions for SHArc were evaluated against conventional planning t

SUBMITTER: Mein S 

PROVIDER: S-EPMC8010580 | biostudies-literature | 2021 May-Jun

REPOSITORIES: biostudies-literature