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Complete remission of metastatic osteosarcoma using combined modality therapy: a retrospective analysis of unselected patients in China.


ABSTRACT:

Background

Complete surgical remission (CSR) is the best predictor of overall survival (OS) for patients with metastatic osteosarcoma. However, metastasectomy has not been widely implemented in China in the last decade due to various factors, and instead, most physicians choose hypofractionated radiotherapy to treat pulmonary lesions. This study aimed to retrospectively evaluate the outcomes of different local treatments for pulmonary lesions and identify the best local therapy strategies for these patients.

Methods

We reviewed the clinical courses of osteosarcoma patients with pulmonary metastases who were initially treated in two sarcoma centres in Beijing, China, from June 1st, 2009, to March 26th, 2020. With a median follow-up of 32.4 (95% confidence interval (CI): 30.8,

SUBMITTER: Xie L 

PROVIDER: S-EPMC8010982 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature