Mortality and Access to Kidney Transplantation in Patients with Sickle Cell Disease-Associated Kidney Failure.

ABSTRACT:

Background and objectives

Patients with sickle cell disease-associated kidney failure have high mortality, which might be lowered by kidney transplantation. However, because they show higher post-transplant mortality compared with patients with other kidney failure etiologies, kidney transplantation remains controversial in this population, potentially limiting their chance of receiving transplantation. We aimed to quantify the decrease in mortality associated with transplantation in this population and determine the chance of receiving transplantation with sickle cell disease as the cause of kidney failure as compared with other etiologies of kidney failure.

Design, setting, participants, & measurements

Using a national registry, we studied all adults with kidney failure wh

SUBMITTER: Bae S 

PROVIDER: S-EPMC8011008 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature