Bacterial community structure alterations within the colorectal cancer gut microbiome.

ABSTRACT:

Background

Colorectal cancer is a leading cause of cancer-related deaths worldwide. The human gut microbiome has become an active area of research for understanding the initiation, progression, and treatment of colorectal cancer. Despite multiple studies having found significant alterations in the carriage of specific bacteria within the gut microbiome of colorectal cancer patients, no single bacterium has been unequivocally connected to all cases. Whether alterations in species carriages are the cause or outcome of cancer formation is still unclear, but what is clear is that focus should be placed on understanding changes to the bacterial community structure within the cancer-associated gut microbiome.

Results

By applying a novel set of analyses on 252 previously published

SUBMITTER: Loftus M 

PROVIDER: S-EPMC8011136 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature