Reference intervals for 26 common biochemical analytes in term neonates in Jilin Province, China.

ABSTRACT:

Background

Biochemical analytes provide information for neonatal disease management and therapy, and population-based reference intervals (RIs) are essential to accurately interpret laboratory test results. This study aimed to establish local RIs for biochemical assays in term neonates.

Methods

A total of 195 healthy term neonates from birth to 3rd day were recruited as reference individuals prospectively. Analytes of 26 common biochemistries were measured using the VITROS 5600 Integrated System. The 3-level nested ANOVA was performed to assess the need for partitioning RIs of each analyte, and RIs were derived by a nonparametric method or robust method. Multiple regression analysis was used to evaluate specific correlations between the analytes and individual characteristic

SUBMITTER: Wang K 

PROVIDER: S-EPMC8011145 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature