Predictors of shortages of opioid analgesics in the US: Are the characteristics of the drug company the missing puzzle piece?

ABSTRACT:

Background

Shortages of opioid analgesics are increasingly common, interfere with patient care and increase healthcare cost. This study characterized the incidence of shortages of opioid analgesics in the period 2015-2019 and evaluated potential predictors to forecast the risk of shortages.

Methods

This was an observational retrospective study using the US Food and Drug Administration (FDA) drug shortages data. All FDA approved opioids were included in the study. Opioid analgesics were identified using the FDA National Drug Codes (NDC) and classified according to the Drug Enforcement Administration (DEA) schedule. We conducted Least Absolute Shrinkage and Selection Operator logistic regression analysis to assess direction of the association between risk of shortage and poten

SUBMITTER: Rodriguez-Monguio R 

PROVIDER: S-EPMC8011730 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature