Exposure to formaldehyde and asthma outcomes: A systematic review, meta-analysis, and economic assessment.

ABSTRACT:

Background

Every major federal regulation in the United States requires an economic analysis estimating its benefits and costs. Benefit-cost analyses related to regulations on formaldehyde exposure have not included asthma in part due to lack of clarity in the strength of the evidence.

Objectives

1) To conduct a systematic review of evidence regarding human exposure to formaldehyde and diagnosis, signs, symptoms, exacerbations, or other measures of asthma in humans; and 2) quantify the annual economic benefit for decreases in formaldehyde exposure.

Methods

We developed and registered a protocol in PROSPERO (Record ID #38766, CRD 42016038766). We conducted a comprehensive search of articles published up to April 1, 2020. We evaluated potential risk of bias for included

SUBMITTER: Lam J 

PROVIDER: S-EPMC8011796 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature