Melanoma risk stratification of individuals with a high-risk naevus phenotype - A pilot study.

ABSTRACT:

Background/objectives

High a naevus counts and atypical naevi are risk factors for cutaneous melanoma. However, many individuals with a high-risk naevus phenotype do not develop melanoma. In this study, we describe the clinical and dermoscopic attributes of naevi associated with melanoma in a high-risk naevus phenotype population.

Methods

This single-centre, hospital-based case-control study included 54 prospectively enrolled adult patients ≥18 years old with a high-risk naevus phenotype (18 cases with a history of melanoma and 36 age- and gender-matched controls without a history of melanoma). We analysed clinical and dermoscopic images of the 20 largest naevi for each participant.

Results

Cases had a higher mean age than controls (48.2 vs. 39.1 years, P = 0.007) but

SUBMITTER: Rishpon A 

PROVIDER: S-EPMC8011832 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature