Activation shift in elderly subjects across functional systems: an fMRI study.

ABSTRACT: The functional specificity of brain areas is diminished with age and accompanied by the recruitment of additional brain regions in healthy older adults. This process has repeatedly been demonstrated within distinct functional domains, in particular the visual system. However, it is yet unclear, whether this phenomenon in healthy aging, i.e., a reduced activation of task-associated areas and increased activation of additional regions, is also present across different functional systems. In the present functional imaging study, comprising 102 healthy subjects, we therefore assessed two distinct tasks engaging the sensory-motor system and the visual attention system, respectively. We found a significant interaction between age and task in the parietal operculum bilaterally. This area as a par

SUBMITTER: Roski C 

PROVIDER: S-EPMC8011857 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature