Influence of unfused cranial bones on magnetoencephalography signals in human infants.

ABSTRACT:

Objective

To clarify the effects of unfused cranial bones on magnetoencephalography (MEG) signals during early development.

Methods

In a simulation study, we compared the MEG signals over a spherical head model with a circular hole mimicking the anterior fontanel to those over the same head model without the fontanel for different head and fontanel sizes with varying skull thickness and conductivity.

Results

The fontanel had small effects according to three indices. The sum of differences in signal over a sensor array due to a fontanel, for example, was < 6% of the sum without the fontanel. However, the fontanel effects were extensive for dipole sources deep in the brain or outside the fontanel for larger fontanels. The effects were comparable in magnitude for tangent

SUBMITTER: Lew S 

PROVIDER: S-EPMC8012008 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature