Sentinel Lymph Node Biopsy in Head and Neck Melanoma: Long-term Outcomes, Prognostic Value, Accuracy, and Safety.

ABSTRACT:

Objective

To evaluate the long-term outcomes of sentinel lymph node biopsy (SLNB) for head and neck cutaneous melanoma (HNCM).

Study design

Retrospective cohort study.

Setting

Tertiary academic medical center.

Subjects and methods

Longitudinal review of a 356-patient cohort with HNCM undergoing SLNB from 1997 to 2007.

Results

Descriptive characteristics included the following: age, 53.5 ± 19 years (mean ± SD); sex, 26.8% female; median follow-up, 4.9 years; and Breslow depth, 2.52 ± 1.87 mm. Overall, 75 (21.1%) patients had a positive SLNB. Among patients undergoing completion lymph node dissection following positive SLNB, 20 (27.4%) had at least 1 additional positive nonsentinel lymph node. Eighteen patients with local control and negative SLNB develope

SUBMITTER: Hanks JE 

PROVIDER: S-EPMC8012010 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature