Molecular characterisation of Mycobacterium avium subsp. paratuberculosis in Australia.

ABSTRACT:

Background

Mycobacterium avium subsp. paratuberculosis (Map) causes Johne's disease (JD), a chronic enteritis widespread in ruminants, resulting in substantial economic losses, especially to the dairy industry. Understanding the genetic diversity of Map in Australia will assist epidemiological studies for tracking disease transmission and identify subtype characteristics for use in development of improved diagnostic typing methods. Here we investigated the phylogenetic relationships of 351 Map isolates and compared different subtyping methods to assess their suitability for use in diagnostics and accuracy.

Results

SNP-based phylogenetic analysis of 228 Australian isolates and 123 publicly available international isolates grouped Type S and Type C strains into two distinct li

SUBMITTER: Hodgeman R 

PROVIDER: S-EPMC8012159 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature